abstract：:Induced pluripotent stem cells (iPSCs) and human embryonic stem cells (hESCs) differentiated into hepatocyte-like cells (HLCs) provide a defined and renewable source of cells for drug screening, toxicology and regenerative medicine. We previously reprogrammed human fetal foreskin fibroblast cells (HFF1) into iPSCs emp...

journal_title：Scientific data

authors： Wruck W,Adjaye J

更新日期：2018-03-13 00:00:00

abstract：:The nuclear receptor estrogen receptor 2 (ESR2, ERβ) modulates cancer cell proliferation and tumor growth, exerting an oncosuppressive role in breast cancer (BC). Interaction proteomics by tandem affinity purification coupled to mass spectrometry was previously applied in BC cells to identify proteins acting in concer...

journal_title：Scientific data

authors： Giurato G,Nassa G,Salvati A,Alexandrova E,Rizzo F,Nyman TA,Weisz A,Tarallo R

更新日期：2018-03-06 00:00:00

abstract：:In 2010, an estimated 860 million people were living in slums worldwide, with around 60 million added to the slum population between 2000 and 2010. In 2011, 200 million people in urban Indian households were considered to live in slums. In order to address and create slum development programmes and poverty alleviation...

journal_title：Scientific data

authors： Roy D,Palavalli B,Menon N,King R,Pfeffer K,Lees M,Sloot PMA

更新日期：2018-01-09 00:00:00

abstract：:We provide a detailed description of a gadoteridol-derivatized lysozyme (gadolinium lysozyme) two-colour serial femtosecond crystallography (SFX) dataset for multiple wavelength anomalous dispersion (MAD) structure determination. The data was collected at the Spring-8 Angstrom Compact free-electron LAser (SACLA) facil...

journal_title：Scientific data

authors： Gorel A,Motomura K,Fukuzawa H,Doak RB,Grünbein ML,Hilpert M,Inoue I,Kloos M,Nass Kovács G,Nango E,Nass K,Roome CM,Shoeman RL,Tanaka R,Tono K,Foucar L,Joti Y,Yabashi M,Iwata S,Ueda K,Barends TRM,Schlichting I

更新日期：2017-12-12 00:00:00

abstract：:This article presents datasets prepared with the aim of helping the evaluation of geospatial matching methods for vector data. These datasets were built up from mapping data produced by official Spanish mapping agencies. The testbed supplied encompasses the three geometry types: point, line and area. Initial datasets ...

journal_title：Scientific data

authors： Xavier EMA,Ariza-López FJ,Ureña-Cámara MA

更新日期：2017-12-05 00:00:00

abstract：:Future highly renewable energy systems will couple to complex weather and climate dynamics. This coupling is generally not captured in detail by the open models developed in the power and energy system communities, where such open models exist. To enable modeling such a future energy system, we describe a dedicated la...

journal_title：Scientific data

authors： Jensen TV,Pinson P

更新日期：2017-11-28 00:00:00

abstract：:This study assessed 24 adult patients, suffering from severe chronic unilateral pain diagnosed as temporomandibular joint (TMJ) disorder (TMD). The full dentate patients had normal occlusion and had never received an occlusal therapy, i.e., were with natural dental evolution/maturation. The following functional and dy...

journal_title：Scientific data

authors： López-Cedrún J,Santana-Mora U,Pombo M,Pérez Del Palomar A,Alonso De la Peña V,Mora MJ,Santana U

更新日期：2017-11-07 00:00:00

abstract：:Today in Scientific Data, two compendia of geochemical and multi-omic sequence information (DNA, RNA, protein) generated over almost a decade of time series monitoring in a seasonally anoxic coastal marine setting are presented to the scientific community. These data descriptors introduce a model ecosystem for the stu...

journal_title：Scientific data

authors： Hallam SJ,Torres-Beltrán M,Hawley AK

更新日期：2017-10-31 00:00:00

abstract：:Metastatic colorectal cancer is a leading cause of cancer death. However, current therapy options are limited to chemotherapy, with the addition of anti-EGFR antibodies for patients with RAS wild-type tumours. Novel drug targets, or drug combinations that induce a synergistic response, would be of great benefit to pat...

journal_title：Scientific data

authors： Williams SP,Barthorpe AS,Lightfoot H,Garnett MJ,McDermott U

更新日期：2017-10-03 00:00:00

abstract：:Understanding of sequence diversity is the cornerstone of analysis of genetic disorders, population genetics, and evolutionary biology. Here, we present an update of our sequencing set to 15,220 Icelanders who we sequenced to an average genome-wide coverage of 34X. We identified 39,020,168 autosomal variants passing G...

journal_title：Scientific data

authors： Jónsson H,Sulem P,Kehr B,Kristmundsdottir S,Zink F,Hjartarson E,Hardarson MT,Hjorleifsson KE,Eggertsson HP,Gudjonsson SA,Ward LD,Arnadottir GA,Helgason EA,Helgason H,Gylfason A,Jonasdottir A,Jonasdottir A,Rafnar T,Bes

更新日期：2017-09-21 00:00:00

abstract：:Olympia oysters are found along the west coast of North America and as the only native oyster species in the region, receive considerable attention with regard to restoration and conservation. Knowledge of genetic structure of this species is essential for resource managers. Here we provide genetic data for three dist...

journal_title：Scientific data

authors： White SJ,Vadopalas B,Silliman K,Roberts SB

更新日期：2017-09-12 00:00:00

abstract：:In the last few decades, data-driven methods have come to dominate many fields of scientific inquiry. Open data and open-source software have enabled the rapid implementation of novel methods to manage and analyze the growing flood of data. However, it has become apparent that many scientific fields exhibit distressin...

journal_title：Scientific data

authors： Pasquier T,Lau MK,Trisovic A,Boose ER,Couturier B,Crosas M,Ellison AM,Gibson V,Jones CR,Seltzer M

更新日期：2017-09-05 00:00:00

abstract：:This corrects the article DOI: 10.1038/sdata.2017.37. ...

journal_title：Scientific data

authors： Jungbluth SP,Amend JP,Rappé MS

更新日期：2017-07-04 00:00:00

abstract：:Climate change has already influenced lake temperatures globally, but understanding future change is challenging. The response of lakes to changing climate drivers is complex due to the nature of lake-atmosphere coupling, ice cover, and stratification. To better understand the diversity of lake responses to climate ch...

journal_title：Scientific data

authors： Winslow LA,Hansen GJA,Read JS,Notaro M

更新日期：2017-04-25 00:00:00

abstract：:Advances in high-throughput sequencing are reshaping how we perceive microbial communities inhabiting the human body, with implications for therapeutic interventions. Several large-scale datasets derived from hundreds of human microbiome samples sourced from multiple studies are now publicly available. However, idiosy...

journal_title：Scientific data

authors： Hahn AS,Altman T,Konwar KM,Hanson NW,Kim D,Relman DA,Dill DL,Hallam SJ

更新日期：2017-04-11 00:00:00

abstract：:Neuroblastoma cell lines are an important and cost-effective model used to study oncogenic drivers of the disease. While many of these cell lines have been previously characterized with SNP, methylation, and/or mRNA expression microarrays, there has not been an effort to comprehensively sequence these cell lines. Here...

journal_title：Scientific data

authors： Harenza JL,Diamond MA,Adams RN,Song MM,Davidson HL,Hart LS,Dent MH,Fortina P,Reynolds CP,Maris JM

更新日期：2017-03-28 00:00:00

abstract：:We describe a screen for cellular response to drugs that makes use of haploid embryonic stem cells. We generated ten libraries of mutants with piggyBac gene trap transposon integrations, totalling approximately 100,000 mutant clones. Random barcode sequences were inserted into the transposon vector to allow the number...

journal_title：Scientific data

authors： Pettitt SJ,Krastev DB,Pemberton HN,Fontebasso Y,Frankum J,Rehman FL,Brough R,Song F,Bajrami I,Rafiq R,Wallberg F,Kozarewa I,Fenwick K,Armisen-Garrido J,Swain A,Gulati A,Campbell J,Ashworth A,Lord CJ

更新日期：2017-03-01 00:00:00

abstract：:The mammalian innate immune system senses many bacterial stimuli through the toll-like receptor (TLR) family. Activation of the TLR4 receptor by bacterial lipopolysaccharide (LPS) is the most widely studied TLR pathway due to its central role in host responses to gram-negative bacterial infection and its contribution ...

journal_title：Scientific data

authors： Sun J,Katz S,Dutta B,Wang Z,Fraser ID

更新日期：2017-03-01 00:00:00

abstract：:Asymptomatic ebolavirus infection could greatly influence transmission dynamics, but there is little consensus on how frequently it occurs or even if it exists. This paper summarises the available evidence on seroprevalence of Ebola, Sudan and Bundibugyo virus IgG in people without known ebolavirus disease. Through sy...

journal_title：Scientific data

authors： Bower H,Glynn JR

更新日期：2017-01-31 00:00:00

abstract：:In this paper we analyse the spatial footprint and temporal clustering of extreme sea level and skew surge events around the UK coast over the last 100 years (1915-2014). The vast majority of the extreme sea level events are generated by moderate, rather than extreme skew surges, combined with spring astronomical high...

journal_title：Scientific data

authors： Haigh ID,Wadey MP,Wahl T,Ozsoy O,Nicholls RJ,Brown JM,Horsburgh K,Gouldby B

更新日期：2016-12-06 00:00:00

abstract：:In angiogenesis with concurrent inflammation, many pathways are activated, some linked to VEGF and others largely VEGF-independent. Pathways involving inflammatory mediators, chemokines, and micro-RNAs may play important roles in maintaining a pro-angiogenic environment or mediating angiogenic regression. Here, we des...

journal_title：Scientific data

authors： Mukwaya A,Lindvall JM,Xeroudaki M,Peebo B,Ali Z,Lennikov A,Jensen LD,Lagali N

更新日期：2016-11-22 00:00:00

abstract：:Populations in resource dependent economies gain well-being from the natural environment, in highly spatially and temporally variable patterns. To collect information on this, we designed and implemented a 1586-household quantitative survey in the southwest coastal zone of Bangladesh. Data were collected on material, ...

journal_title：Scientific data

authors： Adams H,Adger WN,Ahmad S,Ahmed A,Begum D,Lázár AN,Matthews Z,Rahman MM,Streatfield PK

更新日期：2016-11-08 00:00:00

abstract：:Orchids are renowned for their spectacular flowers and ecological adaptations. After the sequencing of the genome of the tropical epiphytic orchid Phalaenopsis equestris, we combined Illumina HiSeq2000 for RNA-Seq and Trinity for de novo assembly to characterize the transcriptomes for 11 diverse P. equestris tissues r...

journal_title：Scientific data

authors： Niu SC,Xu Q,Zhang GQ,Zhang YQ,Tsai WC,Hsu JL,Liang CK,Luo YB,Liu ZJ

更新日期：2016-09-27 00:00:00

abstract：:Tardigrades are ubiquitous microscopic animals that play an important role in the study of metazoan phylogeny. Most terrestrial tardigrades can withstand extreme environments by entering an ametabolic desiccated state termed anhydrobiosis. Due to their small size and the non-axenic nature of laboratory cultures, molec...

journal_title：Scientific data

authors： Arakawa K,Yoshida Y,Tomita M

更新日期：2016-08-16 00:00:00

abstract：:When visual input has conflicting interpretations, conscious perception can alternate spontaneously between these possible interpretations. This is called bistable perception. Previous neuroimaging studies have indicated the involvement of two right parietal areas in resolving perceptual ambiguity (ant-SPLr and post-S...

journal_title：Scientific data

authors： Schauer G,Chang A,Schwartzman D,Rae CL,Iriye H,Seth AK,Kanai R

更新日期：2016-08-16 00:00:00

abstract：:Temporal lobe epilepsy (TLE) can develop from alterations in hippocampal structure and circuit characteristics, and can be modeled in mice by administration of kainic acid (KA). Adult neurogenesis in the dentate gyrus (DG) contributes to hippocampal functions and has been reported to contribute to the development of T...

journal_title：Scientific data

authors： Schouten M,Bielefeld P,Fratantoni SA,Hubens CJ,Piersma SR,Pham TV,Voskuyl RA,Lucassen PJ,Jimenez CR,Fitzsimons CP

更新日期：2016-08-16 00:00:00

abstract：:Bats, including African straw-coloured fruit bats (Eidolon helvum), have been highlighted as reservoirs of many recently emerged zoonotic viruses. This common, widespread and ecologically important species was the focus of longitudinal and continent-wide studies of the epidemiological and ecology of Lagos bat virus, h...

journal_title：Scientific data

authors： Peel AJ,Baker KS,Hayman DT,Suu-Ire R,Breed AC,Gembu GC,Lembo T,Fernández-Loras A,Sargan DR,Fooks AR,Cunningham AA,Wood JL

更新日期：2016-08-01 00:00:00

abstract：:Spatio-temporal data on human population and its driving factors is critical to understanding and responding to population problems. Unfortunately, such spatio-temporal data on a large scale and over the long term are often difficult to obtain. Here, we present a dataset on Chinese population distribution and its driv...

journal_title：Scientific data

authors： Wang L,Chen L

更新日期：2016-07-05 00:00:00

abstract：:Long-term datasets of number and size of lakes over the Tibetan Plateau (TP) are among the most critical components for better understanding the interactions among the cryosphere, hydrosphere, and atmosphere at regional and global scales. Due to the harsh environment and the scarcity of data over the TP, data accumula...

journal_title：Scientific data

authors： Wan W,Long D,Hong Y,Ma Y,Yuan Y,Xiao P,Duan H,Han Z,Gu X

更新日期：2016-06-21 00:00:00

abstract：:Surveys for more than 9,500 households were conducted in the growing seasons 2002/2003 or 2003/2004 in eleven African countries: Burkina Faso, Cameroon, Ghana, Niger and Senegal in western Africa; Egypt in northern Africa; Ethiopia and Kenya in eastern Africa; South Africa, Zambia and Zimbabwe in southern Africa. Hous...

journal_title：Scientific data

authors： Waha K,Zipf B,Kurukulasuriya P,Hassan RM

更新日期：2016-05-24 00:00:00

abstract：:Trait-based approaches advance ecological and evolutionary research because traits provide a strong link to an organism's function and fitness. Trait-based research might lead to a deeper understanding of the functions of, and services provided by, ecosystems, thereby improving management, which is vital in the curren...

journal_title：Scientific data

authors： Madin JS,Anderson KD,Andreasen MH,Bridge TC,Cairns SD,Connolly SR,Darling ES,Diaz M,Falster DS,Franklin EC,Gates RD,Harmer A,Hoogenboom MO,Huang D,Keith SA,Kosnik MA,Kuo CY,Lough JM,Lovelock CE,Luiz O,Martinelli J

更新日期：2016-03-29 00:00:00

abstract：:We present a test-retest dataset for evaluation of long-term reliability of measures from structural and resting-state functional magnetic resonance imaging (sMRI and rfMRI) scans. The repeated scan dataset was collected from 61 healthy adults in two sessions using highly similar imaging parameters at an interval of 1...

journal_title：Scientific data

authors： Huang L,Huang T,Zhen Z,Liu J

更新日期：2016-03-15 00:00:00

abstract：:Land Use Information is a key dataset required to enable an understanding of the changing nature of our landscapes and the associated influences on natural resources and regional communities. The Victorian Land Use Information System (VLUIS) data product has been created within the State Government of Victoria to supp...

journal_title：Scientific data

authors： Morse-McNabb E,Sheffield K,Clark R,Lewis H,Robson S,Cherry D,Williams S

更新日期：2015-11-24 00:00:00

abstract：:The silkmoth chorion was studied extensively by F.C. Kafatos' group for almost 40 years. However, the complete structure of the chorion locus was not obtained in the genome sequence of Bombyx mori published in 2008 due to repetitive sequences, resulting in gaps and an incomplete view of the locus. To obtain the comple...

journal_title：Scientific data

authors： Chen Z,Nohata J,Guo H,Li S,Liu J,Guo Y,Yamamoto K,Kadono-Okuda K,Liu C,Arunkumar KP,Nagaraju J,Zhang Y,Liu S,Labropoulou V,Swevers L,Tsitoura P,Iatrou K,Gopinathan KP,Goldsmith MR,Xia Q,Mita K

更新日期：2015-11-10 00:00:00

abstract：:East Africa is a drought prone, food and water insecure region with a highly variable climate. This complexity makes rainfall estimation challenging, and this challenge is compounded by low rain gauge densities and inhomogeneous monitoring networks. The dearth of observations is particularly problematic over the past ...

journal_title：Scientific data

authors： Funk C,Nicholson SE,Landsfeld M,Klotter D,Peterson P,Harrison L

更新日期：2015-09-29 00:00:00

abstract：:One of the many ways that climate change may affect human health is by altering the nutrient content of food crops. However, previous attempts to study the effects of increased atmospheric CO2 on crop nutrition have been limited by small sample sizes and/or artificial growing conditions. Here we present data from a me...

journal_title：Scientific data

authors： Dietterich LH,Zanobetti A,Kloog I,Huybers P,Leakey AD,Bloom AJ,Carlisle E,Fernando N,Fitzgerald G,Hasegawa T,Holbrook NM,Nelson RL,Norton R,Ottman MJ,Raboy V,Sakai H,Sartor KA,Schwartz J,Seneweera S,Usui Y,Yoshina

更新日期：2015-07-21 00:00:00

abstract：:Geological structures are by nature inaccessible to direct observation. This can cause difficulties in applications where a spatially explicit representation of such structures is required, in particular when modelling fluid migration in geological formations. An increasing trend in recent years has been to use analog...

journal_title：Scientific data

authors： Bayer P,Comunian A,Höyng D,Mariethoz G

更新日期：2015-07-07 00:00:00

abstract：:Studies of chimpanzee vocal communication provide valuable insights into the evolution of communication in complex societies, and also comparative data for understanding the evolution of human language. One particularly valuable dataset of recordings from free-living chimpanzees was collected by Frans X. Plooij and th...

journal_title：Scientific data

authors： Plooij FX,van de Rijt-Plooij H,Fischer M,Wilson ML,Pusey A

更新日期：2015-05-26 00:00:00

abstract：:This article presents data derived from a 36 year-long uninterrupted observational study of amphibian populations living in the city and vicinity of Yekaterinburg, Russia. This area is inhabited by six amphibian species. Based on a degree of anthropogenic transformation, the urban territory is divided into five highly...

journal_title：Scientific data

authors： Vershinin VL,Vershinina SD,Berzin DL,Zmeeva DV,Kinev AV

更新日期：2015-05-12 00:00:00

abstract：:In order to map global disease risk, a geographic database of human Crimean-Congo haemorrhagic fever virus (CCHFV) occurrence was produced by surveying peer-reviewed literature and case reports, as well as informal online sources. Here we present this database, comprising occurrence data linked to geographic point or ...

journal_title：Scientific data

authors： Messina JP,Pigott DM,Duda KA,Brownstein JS,Myers MF,George DB,Hay SI

更新日期：2015-04-14 00:00:00